Ann Dermatol.  2015 Jun;27(3):319-321. 10.5021/ad.2015.27.3.319.

Infundibulocystic Squamous Cell Carcinoma

Affiliations
  • 1Department of Dermatology, Incheon St. Mary's Hospital, School of Medicine, The Catholic University of Korea, Incheon, Korea. leejd@olmh.cuk.ac.kr

Abstract

Infundibulocystic squamous cell carcinoma was first reported in 2008 as a subset of squamous cell carcinoma arising from the infundibulum of the hair follicle and exhibiting infundibular differentiation. It has well-differentiated, less-differentiated, and infiltrative forms. It was thoroughly analyzed in a series of cases in 2011 by Misago et al. and has been redefined to include only the infiltrative form owing to its unique clinical and histological characteristics. Here, we report an interesting case of infundibulocystic squamous cell carcinoma in a 72-year-old man presenting with a mass on the left helix of the ear.

Keyword

Squamous cell carcinoma

MeSH Terms

Aged
Carcinoma, Squamous Cell*
Ear
Hair Follicle
Humans

Figure

  • Fig. 1 A solitary 2-cm, crusted, fleshcolored, and rubbery mass on the left helix.

  • Fig. 2 Histological findings of the excised mass. (A) Infiltrating infundibular canals and radiating cords with multiple cysts in the dermis (H&E, ×40). (B) Multiple cysts filled with laminated keratin in the dermis (H&E, ×40). (C) Neoplasm cords or nests composed of atypical keratinocytes with hyperchromatism, pleomorphism, dyskeratosis, and minimal mitosis (H&E, ×200).


Reference

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