J Korean Neuropsychiatr Assoc.  2016 Aug;55(3):277-285. 10.4306/jknpa.2016.55.3.277.

The Effects of Stress- and Sleep-Related Variables on the Quality of Life in Insomnia Patients

Affiliations
  • 1Department of Psychiatry, Kangwon National University Hospital, Chuncheon, Korea. jhielee@kangwon.ac.kr
  • 2Department of Psychiatry, Yesarang Hospital, Cheongju, Korea.
  • 3Department of Psychiatry, Kangwon National University School of Medicine, Chuncheon, Korea.

Abstract


OBJECTIVES
We examined the effects of sleep variables and emotional factors including stress, anxiety and depression on the quality of life in insomnia patients.
METHODS
We recruited 153 insomnia patients and 96 normal control (NC) subjects who visited three Public Health Centers in Kangwon-do from 2013 until 2015. The Pittsburgh Sleep Quality Index (PSQI), Korean version of Morningness-Eveningness Questionnaire (MEQ-K), Korean version of Epworth Sleepiness Scale, Ford Insomnia Response to Stress Test (FIRST), Hyperarousal Scale (HAS), Perceived Stress Scale (PSS), Anxiety-Sensitivity Index (ASI), Beck Depression Inventory (BDI), and Short Form-12 Health Survey Questionnaire (SF-12) were administered for each subject. We compared the scores of the above scales between the insomnia and control groups, using analysis of covariance to control for age. Stepwise regression analysis assessed the association of these variables with SF-12 scores.
RESULTS
The scores of PSQI, FIRST, HAS, ASI, BDI in insomnia patients were significantly higher than those of NC subjects, but the Mental Component Summary (MCS) scores of SF-12 were lower. Stepwise regression analysis showed the scores of PSS and MEQ-K significantly predicted the MCS scores in NC subjects, and the BDI score predicted scores in insomnia patients.
CONCLUSION
In our study, greater subjective stress and evening preference could explain lower mental quality of life in NC subjects. In insomnia patients, greater depression is an additional factor.

Keyword

Insomnia; Sleep; Stress; Depression; Quality of life

MeSH Terms

Anxiety
Depression
Exercise Test
Gangwon-do
Health Surveys
Humans
Public Health
Quality of Life*
Sleep Initiation and Maintenance Disorders*
Weights and Measures

Reference

1. Fernandez-Mendoza J, Vgontzas AN. Insomnia and its impact on physical and mental health. Curr Psychiatry Rep. 2013; 15:418.
Article
2. Ohayon MM. Epidemiology of insomnia: what we know and what we still need to learn. Sleep Med Rev. 2002; 6:97–111.
Article
3. Cho SJ, Oh DH, Park YC, Nam JH, Kim SH. The clinical association between the prevalence of insomnia and physical and psychiatric disorders in two areas of Gyeonggi Province of South Korea. J Korean Neuropsychiatr Assoc. 2016; 55:41–50.
Article
4. Baernholdt M, Yan G, Hinton I, Rose K, Mattos M. Quality of life in rural and urban adults 65 years and older: findings from the National Health and Nutrition Examination survey. J Rural Health. 2012; 28:339–347.
Article
5. Hong SB. Sleep disorders medicine. J Korean Med Assoc. 2013; 56:410–422.
Article
6. Park HS, Joo EY, Hong SB. Sleep onset insomnia. J Korean Sleep Soc. 2009; 6:74–85.
Article
7. Smith S, Sullivan K, Hopkins W, Douglas J. Frequency of insomnia report in patients with obstructive sleep apnoea hypopnea syndrome (OSAHS). Sleep Med. 2004; 5:449–456.
Article
8. Guilleminault C, Rosekind M. The arousal threshold: sleep deprivation, sleep fragmentation, and obstructive sleep apnea syndrome. Bull Eur Physiopathol Respir. 1981; 17:341–349.
9. Stoohs RA, Dement WC. Snoring and sleep-related breathing abnormality during partial sleep deprivation. N Engl J Med. 1993; 328:1279.
Article
10. Persson HE, Svanborg E. Sleep deprivation worsens obstructive sleep apnea. Comparison between diurnal and nocturnal polysomnography. Chest. 1996; 109:645–650.
11. Chung KF. Insomnia subtypes and their relationships to daytime sleepiness in patients with obstructive sleep apnea. Respiration. 2005; 72:460–465.
Article
12. Ferri R, Gschliesser V, Frauscher B, Poewe W, Högl B. Periodic leg movements during sleep and periodic limb movement disorder in patients presenting with unexplained insomnia. Clin Neurophysiol. 2009; 120:257–263.
Article
13. Roepke SE, Duffy JF. Differential impact of chronotype on weekday and weekend sleep timing and duration. Nat Sci Sleep. 2010; 2010:213–220.
14. Mai E, Buysse DJ. Insomnia: prevalence, impact, pathogenesis, differential diagnosis, and evaluation. Sleep Med Clin. 2008; 3:167–174.
Article
15. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Washington DC: American Psychiatric Publishing;2013. p. 361–422.
16. Morin CM, Bélanger L, LeBlanc M, Ivers H, Savard J, Espie CA, et al. The natural history of insomnia: a population-based 3-year longitudinal study. Arch Intern Med. 2009; 169:447–453.
17. LeBlanc M, Beaulieu-Bonneau S, Mérette C, Savard J, Ivers H, Morin CM. Psychological and health-related quality of life factors associated with insomnia in a population-based sample. J Psychosom Res. 2007; 63:157–166.
Article
18. Zammit GK, Weiner J, Damato N, Sillup GP, McMillan CA. Quality of life in people with insomnia. Sleep. 1999; 22:Suppl 2. S379–S385.
19. Stein MB, Barrett-Connor E. Quality of life in older adults receiving medications for anxiety, depression, or insomnia: findings from a community-based study. Am J Geriatr Psychiatry. 2002; 10:568–574.
Article
20. Björnsdóttir E, Janson C, Gíslason T, Sigurdsson JF, Pack AI, Gehrman P, et al. Insomnia in untreated sleep apnea patients compared to controls. J Sleep Res. 2012; 21:131–138.
Article
21. Cheng KK, Lee DT. Effects of pain, fatigue, insomnia, and mood disturbance on functional status and quality of life of elderly patients with cancer. Crit Rev Oncol Hematol. 2011; 78:127–137.
Article
22. Johansson P, Arestedt K, Alehagen U, Svanborg E, Dahlström U, Broström A. Sleep disordered breathing, insomnia, and health related quality of life -- a comparison between age and gender matched elderly with heart failure or without cardiovascular disease. Eur J Cardiovasc Nurs. 2010; 9:108–117.
Article
23. Caap-Ahlgren M, Dehlin O. Insomnia and depressive symptoms in patients with Parkinson's disease. Relationship to health-related quality of life. An interview study of patients living at home. Arch Gerontol Geriatr. 2001; 32:23–33.
24. Suka M, Yoshida K, Sugimori H. Persistent insomnia is a predictor of hypertension in Japanese male workers. J Occup Health. 2003; 45:344–350.
Article
25. Bonnet MH, Arand DL. Heart rate variability in insomniacs and matched normal sleepers. Psychosom Med. 1998; 60:610–615.
Article
26. Bonnet MH, Arand DL. 24-hour metabolic rate in insomniacs and matched normal sleepers. Sleep. 1995; 18:581–588.
Article
27. Lee E, Cho HJ, Olmstead R, Levin MJ, Oxman MN, Irwin MR. Persistent sleep disturbance: a risk factor for recurrent depression in community-dwelling older adults. Sleep. 2013; 36:1685–1691.
Article
28. Buysse DJ, Angst J, Gamma A, Ajdacic V, Eich D, Rössler W. Prevalence, course, and comorbidity of insomnia and depression in young adults. Sleep. 2008; 31:473–480.
Article
29. Vgontzas AN, Liao D, Pejovic S, Calhoun S, Karataraki M, Basta M, et al. Insomnia with short sleep duration and mortality: the Penn State cohort. Sleep. 2010; 33:1159–1164.
Article
30. Kwon SM, Seo JS, Yang SK, Choi JY, Yim HW, Jo SJ, et al. A field study of the conditions of the elderly in rural community; the correlation between of sleep quality and quality of life. J Korean Neuropsychiatr Assoc. 2012; 51:119–126.
Article
31. Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989; 28:193–213.
Article
32. Lee JH, Kim SJ, Lee SY, Jang KH, Kim IS, Duffy JF. Reliability and validity of the Korean version of Morningness-Eveningness Questionnaire in adults aged 20-39 years. Chronobiol Int. 2014; 31:479–486.
Article
33. Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991; 14:540–545.
Article
34. Cho YW, Lee JH, Son HK, Lee SH, Shin C, Johns MW. The reliability and validity of the Korean version of the Epworth sleepiness scale. Sleep Breath. 2011; 15:377–384.
Article
35. Drake C, Richardson G, Roehrs T, Scofield H, Roth T. Vulnerability to stress-related sleep disturbance and hyperarousal. Sleep. 2004; 27:285–291.
Article
36. Pavlova M, Berg O, Gleason R, Walker F, Roberts S, Regestein Q. Self-reported hyperarousal traits among insomnia patients. J Psychosom Res. 2001; 51:435–441.
Article
37. Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983; 24:385–396.
Article
38. Reiss S, Peterson RA, Gursky DM, McNally RJ. Anxiety sensitivity, anxiety frequency and the prediction of fearfulness. Behav Res Ther. 1986; 24:1–8.
Article
39. Lee YH, Song JY. A study of the reliability and the validity of the BDI, SDS, and MMPI-D Scales. Korean J Clin Psychol. 1991; 10:98–113.
40. Ware J Jr, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996; 34:220–233.
41. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Text revision. Washington, DC: American Psychiatric Association;2000.
42. American Academy of Sleep Medicine. International classification of sleep disorders, diagnostic and coding manual. 2nd ed. Westchester, IL: American Academy of Sleep Medicine;2005.
43. Ahn DH. Insomnia: causes and diagnosis. Hanyang Med Rev. 2013; 33:203–209.
Article
44. Ohayon MM, Caulet M, Priest RG, Guilleminault C. DSM-IV and ICSD-90 insomnia symptoms and sleep dissatisfaction. Br J Psychiatry. 1997; 171:382–388.
Article
45. Jang CH, Kim SH, Oh DH. Cognitive behavioral therapy of insomnia. Hanyang Med Rev. 2013; 33:210–215.
Article
46. Pigeon WR, Perlis ML. Sleep homeostasis in primary insomnia. Sleep Med Rev. 2006; 10:247–254.
Article
47. Calkins AW, Hearon BA, Capozzoli MC, Otto MW. Psychosocial predictors of sleep dysfunction: the role of anxiety sensitivity, dysfunctional beliefs, and neuroticism. Behav Sleep Med. 2013; 11:133–143.
Article
48. Ford DE, Kamerow DB. Epidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention? JAMA. 1989; 262:1479–1484.
Article
49. Perlis ML, Giles DE, Buysse DJ, Tu X, Kupfer DJ. Self-reported sleep disturbance as a prodromal symptom in recurrent depression. J Affect Disord. 1997; 42:209–212.
Article
50. Ohayon MM, Roth T. Place of chronic insomnia in the course of depressive and anxiety disorders. J Psychiatr Res. 2003; 37:9–15.
Article
51. Stein MB, Belik SL, Jacobi F, Sareen J. Impairment associated with sleep problems in the community: relationship to physical and mental health comorbidity. Psychosom Med. 2008; 70:913–919.
Article
52. Clark MM, Warren BA, Hagen PT, Johnson BD, Jenkins SM, Werneburg BL, et al. Stress level, health behaviors, and quality of life in employees joining a wellness center. Am J Health Promot. 2011; 26:21–25.
Article
53. Kim BR, Park KS, Lee JS, Kim BJ, Chun JH. Factors related to depression symptom and the influence of depression symptom on self-rated health status, outpatient health service utilization and quality of life. Korean J Health Educ Promot. 2011; 28:81–92.
54. Simon GE. Social and economic burden of mood disorders. Biol Psychiatry. 2003; 54:208–215.
Article
55. Léger D, Scheuermaier K, Philip P, Paillard M, Guilleminault C. SF-36: evaluation of quality of life in severe and mild insomniacs compared with good sleepers. Psychosom Med. 2001; 63:49–55.
Article
56. Jankowski KS. Morningness/eveningness and satisfaction with life in a Polish sample. Chronobiol Int. 2012; 29:780–785.
Article
57. Díaz-Morales JF, Jankowski KS, Vollmer C, Randler C. Morningness and life satisfaction: further evidence from Spain. Chronobiol Int. 2013; 30:1283–1285.
Article
58. Song J, Merskey H, Noh S. The effect of controlling for anxiety and depression upon the threshold for pressure pain in three comparison groups. J Musculoskel Pain. 1993; 1:73–88.
Article
59. Simon GE, VonKorff M, Piccinelli M, Fullerton C, Ormel J. An international study of the relation between somatic symptoms and depression. N Engl J Med. 1999; 341:1329–1335.
Article
60. Jun JY, Kim SJ, Lee YJ, Cho SJ. Effect of major depressive disorder and insomnia on somatization. Sleep Med Psychophysiol. 2012; 19:84–88.
61. Katz DA, McHorney CA. The relationship between insomnia and health-related quality of life in patients with chronic illness. J Fam Pract. 2002; 51:229–235.
62. Aritake S, Asaoka S, Kagimura T, Shimura A, Futenma K, Komada Y, et al. Internet-based survey of factors associated with subjective feeling of insomnia, depression, and low health-related quality of life among Japanese adults with sleep difficulty. Int J Behav Med. 2015; 22:233–238.
Article
63. Lis CG, Gupta D, Grutsch JF. The relationship between insomnia and patient satisfaction with quality of life in cancer. Support Care Cancer. 2008; 16:261–266.
Article
Full Text Links
  • JKNA
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr