J Korean Ophthalmol Soc.  2016 Aug;57(8):1316-1319. 10.3341/jkos.2016.57.8.1316.

Use of Video-oculography in the Diagnosis of Superior Oblique Myokymia

Affiliations
  • 1Department of Ophthalmology, Chonbuk National University Medical School, Jeonju, Korea. ahnmin@jbnu.ac.kr
  • 2Research Institute of Clinical Medicine, Chonbuk National University, Jeonju, Korea.
  • 3Biomedical Research Institute, Chonbuk National University Hospital, Jeonju, Korea.

Abstract

PURPOSE
Superior oblique myokymia is intermittent spontaneous contractions of the superior oblique muscle presenting as rapid and small-amplitude intorsions and depressions of the eye. The authors report a case of superior oblique myokymia that was objectively and quantitatively diagnosed with slit lamp examination and video-oculography and completely resolved with medical treatment.
CASE SUMMARY
A 44-year-old woman presented with a seven-year history of intermittent oscillopsia which continued for few seconds. She had no history of head trauma or systemic ocular disease, and the anterior segment and fundus examination were unremarkable. Right eye intorsion lasting for a few seconds as detected by slit lamp examination. Eye movements were recorded using video-oculography, which showed a torsional nystagmus of 5 to 10 degrees with 2 to 5 vertical components in the right eye. Based on these findings, the patient was diagnosed with superior oblique myokymia. The patient was prescribed topical timolol ophthalmic solution, one drop twice per day, but the symptoms persisted. Timolol ophthalmic solution was stopped and replaced with carbamazepine, 200 mg twice a day, which resolved her symptoms.
CONCLUSIONS
Slit lamp examination and video-oculography can be used as objective and quantitative diagnostic tools in order to confirmed a diagnosis and lead to proper treatment.

Keyword

Carbamazepine; Slit lamp examination; Superior oblique myokymia; Video-oculography

MeSH Terms

Adult
Carbamazepine
Craniocerebral Trauma
Depression
Diagnosis*
Eye Movements
Female
Humans
Slit Lamp
Timolol
Trochlear Nerve Diseases*
Carbamazepine
Timolol

Figure

  • Figure 1. Slit lamp examination of the patient. (A) The patient's right eye before the intorsion. (B) The patient's right eye after the intorsion. The angle difference between (A) and (B) is about 7 degree, therefore about 7 degree intorsion was occurred. Iris crypts (arrowheads) movements help to detect intorsion.

  • Figure 2. Video-oculography of the patient. The oculography shows superior oblique myokymia (arrows), evident in the vertical (vertical position of right eye [RV]) and torsional (torsional position of right eye [RT]) records of only the right eye. Horizontal component is time measured by second, vertical component is position measured by degree. LH = horizontal position of left eye, RH = horizontal position of left eye, LV = vertical position of left eye, LT = torsional position of left eye.


Reference

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