J Korean Neurol Assoc.  1985 Dec;3(2):142-153.

An Experimental Study on Velocity Wave Form Analysis in the Diagnosis of Carotid Artery Occlusive Lesion

Affiliations
  • 1Department of Neurology, Seoul National University.

Abstract

This experimental study was performed to evaluate the correlation between the stenosis of common carotid artery and the change of velocity wave form in sixteen mongrel dogs. With continuous directional Doppler the velocity waves were recorded from the common carotid artery, which was experimentally stenosed by the graded constrictor. Grouped according to carotid angiogram, there were 16 normals(I), 21 stenoses of less than 35%(II), 16 stenoses of 36-59%(III), 10 stnoses of 60-79%(IV), and 10 stenoses of more than 80%(V). From the analysis of carotid artery velocity tracings, six most discriminating variables were obtained, which were statistically significant between intergroup comparison except between group I and group II. Four best fit discriminant equations for group II, III, IV, or V were derived through the analysis of the combination of these six variables. Using these equations and the values for six variables, the overall accuracy rate of placing it into appropriate group was 84.2%. The accuracy rate of separating normal, stenosis less than 60%, and stenosis more than 60% was 94.8%. The carotid stenosis of 36-59% (group III) showed some change of carotid velocity wave form and could be diagnosed appropriately using the velocity wave form analysis. Therefore it is concluded that the velocity wave form anlaysis would be a useful and handy mehtod to evaluate the occlusive carotid artery disease.

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