J Korean Neuropsychiatr Assoc.  2012 Sep;51(5):255-262.

Relationships between Cigarette Smoking and Socio-Demographic and Clinical Characteristics in Patients with Schizophrenia in South Korea

Affiliations
  • 1Department of Psychiatry, Inha University School of Medicine, Inha University Hospital, Incheon, Korea. kce320@inha.ac.kr
  • 2Department of Psychiatry, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon, Korea.
  • 3Department of Psychiatry, Dongguk University College of Medicine, Ilsan Hospital, Goyang, Korea.
  • 4Department of Psychiatry, Chonnam National University College of Medicine, Chonnam National University Hospital, Gwangju, Korea.
  • 5Department of Psychiatry, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.
  • 6Department of Psychiatry, Seoul National Hospital, Seoul, Korea.
  • 7Department of Psychiatry, The Catholic University of Korea College of Medicine, St. Vincent's Hospital, Suwon, Korea.
  • 8Department of Psychiatry, Kyunghee University School of Medicine, Kyunghee University Medical Center, Seoul, Korea.
  • 9Department of Psychiatry, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea.
  • 10Department of Psychiatry, Chung-Ang University College of Medicine, Chung-Ang University Hospital, Seoul, Korea.
  • 11Department of Psychiatry, Yonsei University Wonju College of Medicine, Wonju Christian Hospital, Wonju, Korea.

Abstract


OBJECTIVES
In patients with schizophrenia, the prevalence of smoking is significantly higher than that of the general population. This study aimed to evaluate the relationships between cigarette smoking and socio-demographic and clinical characteristics in patients with schizophrenia in South Korea.
METHODS
Post analysis of 2008-2009 three multi-center studies on the paliperidone extended-release switching was performed. A total of 509 patients with a diagnosis of schizophrenia were recruited and interviewed regarding socio-demographic variables, smoking characteristics. Krawiecka Scale, Clinical Global Impression-Schizophrenia-Severity, Clinical Global Impression-Schizophrenia-Improvement, and Personal and Social Performance Scale were used to evaluate psychological disturbance. Safety assessments included adverse events, evaluation of extrapyramidal symptoms using the Drug Induced Extra Pyramidal Symptoms Scale, and laboratory tests.
RESULTS
The results revealed that the prevalence of smoking in Korean patients with schizophrenia is significantly higher than that of the general population. Male, patients with occupation, and paranoid type showed higher rate of smoking and smokers with schizophrenia had higher rates of overweight, thick waist, high blood pressure than non-smokers with schizophrenia. The results revealed that smokers with schizophrenia had higher rating scales of negative and cognitive symptoms.
CONCLUSION
From this study, we reported significant relationships between cigarette smoking and socio-demographic and clinical characteristics in patients with schizophrenia in South Korea. More studies will be needed to evaluate the association between cigarette consumption and schizophrenia, effect of smoking according to the antipsychotics, mechanism of nicotine on schizophrenia.

Keyword

Schizophrenia; Cigarrette; Smoking; Negative symptom; Cognitive symptom
Full Text Links
  • JKNA
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr