J Korean Neuropsychiatr Assoc.  2006 Jan;45(1):42-48.

Non-Relapse Rate in a 24 Week Follow-up Clinical Study with Korean Male Alcohol-Dependent Patients

  • 1Department of Psychiatry, Pusan National University, Busan, Korea. sungkim@pusan.ac.kr
  • 2Department of Psychiatry, College of Medicine, Yonsei University, Seoul, Korea.
  • 3Department of Neuropsychiatry, Maryknoll Hospital, Busan, Korea.
  • 4Department of Psychiatry, National Health Insurance Corporation Ilsan Hospital, Ilsan, Korea.
  • 5Department of Neuropsychiatry, Hallym University, Seoul, Korea.
  • 6Department of Psychiatry, St. Andrew's Neuropsychiatric Hospital, Icheon, Korea.
  • 7Department of Psychiatry, Busan Daenam Hospital, Busan, Korea.
  • 8Department of Psychiatry, Bongseng Memorial Hospital, Busan, Korea.
  • 9Medical Research Institute, Pusan National University Hospital, Busan, Korea.
  • 10Division of Management Information Science, Dong-A University, Busan, Korea.


In order to provide useful data for the further clinical studies with Korean alcohol-dependent patients, enrollment and non-relapse rates were investigated while alcohol-dependent patients were followed up for 24 weeks.
The subjects of this study were alcohol-dependent male patients who, for the first time, visited a hospital among 3 groups of hospitals, University Hospital, General Hospital or Mental Hospital, or those who needed to be followed up after discharge from those hospitals. After assigning 12 subjects to each hospital, we investigated enrollment and non-relapse rates while cognitive-behavioral therapy and pharmacotherapy were provided.
1) Forty-eight patients were enrolled and the rate of enrollment was 36.4%. The enrollment rate in the University Hospital group was 52.1%, in the General Hospital group 50.0%, and in the Mental Hospital group 10.4%. 2) In 48 patients, non-relapse rate was 27.1% at 12 week and 18.8% at 24 weeks after starting follow-up. It was 24.4% and 20.0% at 12 and 24 weeks, repectively, in the University Hospital group while the General Hospital group showed 33.3% and 16.7%, respectively, and the Mental Hospital Group showed 20.0% at both 12 and 24 weeks.
These results provide important data for further clinical studies of Korean alcohol-dependent patients.


Alcohol dependence; Clinical study; Non-relapse rate; Enrollment rate
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