J Korean Ophthalmol Soc.  2015 Jun;56(6):911-916. 10.3341/jkos.2015.56.6.911.

Effect of Prior Cataract Surgery on the Clinical Outcome of Selective Laser Trabeculoplasty

• Park HJ
• Park JW

• KMID: 2339157
• DOI: http://doi.org/10.3341/jkos.2015.56.6.911

Abstract

PURPOSE
To compare the efficacy of selective laser trabeculoplasty (SLT) in phakic and pseudophakic eyes in primary open-angle glaucoma.
METHODS
Charts of 55 phakic eyes and 24 pseudophakic eyes that underwent 360-degree SLT were retrospectively reviewed. Intraocular pressure (IOP) was measured before SLT and 1 week, 1, 3, 6, 9, 12, 18 and 24 months after SLT. Treatment success was defined as IOP reduction > or = 20% without additional medications, laser or glaucoma surgery. Mean IOP change, mean percentage of IOP reduction and success rates of phakic and pseudophakic eyes were compared.
RESULTS
Mean percentage of IOP reduction after SLT at 1 week and 1, 3, 6, 9, 12, 18, and 24 months were 18.8%, 23.9%, 24.6%, 23.3%, 24.0%, 22.1%, 20.8%, and 17.9%, respectively, in the phakic group and 15.7%, 22.3%, 23.7%, 25.3%, 25.6%, 25.2%, 21.9%, and 19.3%, respectively, in the pseudophakic group. Success rates were 57.6 +/- 11.9% in the phakic group and 61.3 +/- 10.4% in the pseudophakic group. No statistically significant differences in IOP change, percentage of IOP reduction, and success rates were observed between the groups at each time point after SLT (p > 0.05).
CONCLUSIONS
Application of 360-degree SLT appears an efficient treatment option for the management of phakic and pseudophakic open-angle glaucoma. Evaluating the success of SLT 1 month postoperatively may be premature.

Keyword

Cataract surgery; Intraocular pressure reduction; Primary open angle glaucoma; Selective laser trabeculoplasty

MeSH Terms

Cataract*
Glaucoma
Glaucoma, Open-Angle
Intraocular Pressure
Retrospective Studies
Trabeculectomy*

Figure

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  Figure 1. Mean IOP after selective laser trabeculoplasty for phakic and pseudophakic eyes. The numbers on graph indicates p-value at each time point. IOP ＝ indicates intraocular pressure.

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  Figure 2. Mean percentage decrease in IOP from baseline for pseudophakic and phakic eyes. The numbers on graph indicates p-value at each time point. IOP ＝ indicates intraocular pressure.

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  Figure 3. Success rate (≥ 20% intraocular pressure decrease) for phakic and pseudophakic eyes. The numbers on graph indicates p-value at each time point.

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  Figure 4. In the Kaplan-Meier chart for phakic and pseudophakic eyes using the definition of success, the course of the curves was dispersed. There were not statistically significant differences between the survival curves in the follow-up period (log-rank test, p＝0.933).

Reference

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