J Korean Ophthalmol Soc.  2010 Mar;51(3):463-468.

Bilateral Serous Retinal Detachment Associated With Alport's Syndrome

• Song YB
• Park SP

Abstract

PURPOSE
To report a case of bilateral serous retinal detachment associated with Alport's syndrome that resolved following intensive blood pressure control and electrolyte imbalance correction.
CASE SUMMARY
A 50-year-old male patient presented with bilateral lenticonus and bilateral serous retinal detachment. Bilateral serous retinal detachment with retinal flecks characteristic of Alport's syndrome appeared along with the development of chronic renal failure and hypertension. The following kidney biopsy revealed Alport's syndrome. After 14 days, the serous detachment resolved and vision recovered following intensive blood pressure control and electrolyte imbalance correction fundus and FA results were nearly normal.
CONCLUSIONS
In this case, bilateral serous retinal detachment in Alport's syndrome resolved with intensive blood pressure control and electrolyte imbalance correction. To the author's knowledge, this is the first case in South Korea with documentation of the onset and resolution of bilateral serous retinal detachment in Alport's syndrome.

Keyword

Alport's syndrome; Serous retinal detachment

MeSH Terms

Biopsy
Blood Pressure
Humans
Hypertension
Kidney
Kidney Failure, Chronic
Male
Middle Aged
Nephritis, Hereditary
Republic of Korea
Retinal Detachment
Retinaldehyde
Vision, Ocular
Zinc Phosphate Cement
Retinaldehyde
Zinc Phosphate Cement

Figure

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  Figure 1. Bilateral anterior lenticonus was shown on slit-lamp examination.

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  Figure 2. The typical pictures of a drop of oil in water “oil-globule”.

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  Figure 3. Bilateral perimacular flecks with serous retinal detachment were shown.

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  Figure 4. Bilateral serous retinal detachment was found on OCT.

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  Figure 5. The following kidney biopsy revealed it to be Alport's syndrome; Stars indicate, from above, diffuse foot process effacement, compressed glomerular capillary lumina and GBMs increased in thickness and irregular wrinkled contours, respectively.

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  Figure 6. The serous retinal detachment resolved and the vision recovered following intensive blood pressure control and electrolyte imbalance correction.

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  Figure 7. Fluorescein angiogram findings were nearly normal after the serous retinal detachment resolved.

Reference

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