J Korean Ophthalmol Soc.  1998 Sep;39(9):1909-1914.

Dacryocystorhinostomy with Intraoperative Mitomycin C

Affiliations
  • 1Department of Ophthalmology, Seoul Adventist Hospital, Seoul, Korea.

Abstract

Nowadays endscopic transnasal dacryocystorhinostomy(DCR) has been done popularly in patients who had epiphora chronically because of lacrimal obstruction. The most frequent cause of DCR failure is obstruction of osteotomy site due to formation of granuloma. We used the mitomycin C to suppress proliferation of fibroblast to increase success rate. Between July 1996 and september 1997, 15 patients(16 eyes) who had visited ophthalmology department in Seoul Advantist Hospital made went endoscopic transnasal DCR and packed merocel socked with 0.2mg/ml between 3 months to 18 months(mean 11.5 months). One case showed recurrent epiphora 2 months after surgery, and success rate was 94%. In conclusion, endoscopic transnasal DCR with Mitomycin C should be considered to suppress proliferation of granuloma and increase success rate.

Keyword

Endoscopic transnasal DCR; Granuloma; Mitomycin C

MeSH Terms

Dacryocystorhinostomy*
Fibroblasts
Granuloma
Humans
Lacrimal Apparatus Diseases
Mitomycin*
Ophthalmology
Osteotomy
Seoul
Mitomycin
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