J Korean Ophthalmol Soc.
1987 Jun;28(3):523-529.
Treatment of Blepharospasm with Botulinum A Toxin
- Affiliations
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- 1The Mt. Sinai Medical Center Cleveland, Ohio, USA.
- 2Division of Ophthalmology Eulji Hospital, Seoul, Korea.
- 3Division of Ophthalmology, The Mt. Sinai Medical Center, Ohio, USA.
- 4Case Western Reserve University, USA.
- 5Oculoplastics Clinic University, Hospitals of Cleveland, Cleveland, Ohio, USA.
Abstract
- Thirty-nine patients with blepharospasm were treated with botulinum A toxin. Twenty-six patients had essential blepharospasm, and thirteen had hemifacial spasm. A total of 113 injections were given, and average follow-up was 14.6 months. The mean preinjection spasm intensity was 2.9+, and the mean post-injection spasm intensity was 0.7+. The mean interval between injections was 4.4 months. The treatment was effective, although transient, in all patients with essential blepharospasm and hemifacial spasm. The toxin had a prolonged effect on the patients who had previously undergone muscle stripping proced ure. The side effects were mild, transient, and local.
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