J Korean Orthop Assoc.  2011 Apr;46(2):158-161.

Development of Conventional Osteosarcoma after 13 Years Continuous Disease-free Survival of Periosteal Osteosarcoma

• Kong CB
• Hong Y
• Koh JS
• Jeon DG

Abstract

Periosteal osteosarcoma is a rare variant of osteosarcoma and has represented 1-2% of all osteosarcomas. Most local recurrences or progression to metastatic disease occurred within the first 3 years after presentation and lung metastasis is more common than bony metastasis. We describe a periosteal osteosarcoma of tibia patient who developed conventional osteosarcoma of proximal humerus after 13 years from the completion of treatment.

Keyword

primary malignant bone tumor; periosteal osteosarcoma; conventional osteosarcoma

MeSH Terms

Disease-Free Survival
Humans
Humerus
Lung
Neoplasm Metastasis
Osteosarcoma
Recurrence
Tibia

Figure

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  Figure 1 (A) Plain anteroposterior and lateral radiographs of right tibia of a 10-year-old boy show bony lesion arising from surface of bone. Marrow does not appear to be involved. (B) MR images demonstrate lesion arising from surface of bone. Marrow does not appear to be involoved. (C) Photomicrograph shows that lobules of malignant cartilage are separated by malignant spindle cells producing osteoid. (D) Radiographs show the reconstructed tibia using bone cement with multiple ender nails.

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  Figure 2 (A) Anteroposterior radiograph of left humerus shows osteosclerotic lesion involving epiphysis of head and proximal meta-diaphysis. Note periosteal reaction of medial aspect of proximal humerus. (B) The left shoulder T2-weighted MR coronal image demonstrates tumor within bone and soft tissue. (C) Enhanced T1-weighted MR coronal image shows heterogeneous enhancement. (D) Photomicrograph reveals the conventional osteoblastic osteosarcoma.

Reference

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