J Korean Pediatr Soc.  1996 Oct;39(10):1443-1447.

Subacute Necrotizing Lymphadenitis in a 3 Year-Old Male Child

  • 1Department of Pediatrics, College of Medicine, Hallym University, Seoul, Korea.
  • 2Department of Pathology, College of Medicine, Hallym University, Seoul, Korea.


Subacute necrotizing lymphadenitis is a benign form of lymphadenitis that was first described in Japan by Kikuchi in 1972. It mainly affects young women and usually manifests as fever and lymphadenopathy. Although it is a benign self-limited lymphadenitis, it has been misdiagnosed as malignant lymphoma. Histologically, involved lymph nodes contain a necrotizing process characterized by patch, well-circumscribed area with eosinophilic fibrinoid material. There is a striking degree of karyorrhexis and an absence of granulocyte with paucity of plasma cell. We expereinced a case of subacute necrotizing lymphadenitis in a 3 year old boy. There was spontaneous resolution of fever and lymphadenopathy, and now he keeps doing well.


Subacute necrotizing lymphadenitis; Kikuchi's disease
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