J Korean Soc Emerg Med.  2010 Apr;21(2):278-281.

Neuroleptic Malignant Syndrome Complicated with Acute Renal Failure Secondary to Quetiapine: A Case Report

Affiliations
  • 1Department of Emergency Medicine, Dankook University Hospital, Cheonan, Korea. holytiger@hanmail.net

Abstract

Neuroleptic malignant syndrome (NMS) is an idiosyncratic, life-threatening complication of treatment with antipsychotic drugs, and this is characterized by fever, severe muscle rigidity and changes of the autonomic nervous system and mental status changes. We present the case of a 19-year-old woman with neuroleptic malignant syndrome that was complicated with acute renal failure secondary to quetiapine overdose. Emergency physicians should keep in mind the possibility of NMS when evaluating patients who present with fever.

Keyword

Neuroleptic malignant syndrome; Antipsychotic agents; Kidney failure; Acute

MeSH Terms

Acute Kidney Injury
Antipsychotic Agents
Autonomic Nervous System
Dibenzothiazepines
Emergencies
Female
Fever
Humans
Muscle Rigidity
Neuroleptic Malignant Syndrome
Renal Insufficiency
Young Adult
Quetiapine Fumarate
Antipsychotic Agents
Dibenzothiazepines
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