J Korean Diabetes.  2013 Mar;14(1):23-26.

Glycemic Control in Diabetic Patients with Diabetic Nephropathy

Affiliations
  • 1Department of Internal Medicine, Inje University College of Medicine, Goyang, Korea. jhnoh@paik.ac.kr

Abstract

Diabetes mellitus is a leading cause of kidney disease; nearly one-third of patients with diabetes develop nephropathy. Several trials assessed the effect of intensive glycemic control in diabetic patients and provided strong evidence that intensive therapy reduces the incidence and progression of diabetic nephropathy, especially microalbuminuria, an early marker of diabetic nephropathy. The presence of impaired kidney function should influence selection, dosing, and monitoring of hypoglycemic agents. This article reviews the effects of intensive glycemic control on the development and progression of diabetic nephropathy and the clinical use of antidiabetic therapies in patients with chronic kidney disease.

Keyword

Glycemic control; Diabetic nephropathy
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