Korean J Clin Neurophysiol.  2016 Jun;18(1):1-6. 10.14253/kjcn.2016.18.1.1.

Relation of Bony Carotid Canal Diameter and Clinical Manifestations in Patients with Moyamoya Disease

• Ahn SH
• Song HK
• Kim CH
• Jang MU
• Sohn JH
• Choi HC

• KMID: 2328820
• DOI: http://doi.org/10.14253/kjcn.2016.18.1.1

Abstract

BACKGROUND
Moyamoya disease is characterized by a progressive stenosis or occlusion of the intracranial internal carotid artery and/or the proximal portion of the anterior cerebral artery and middle cerebral artery. Whether the onset time was childhood or adulthood, the bony carotid canal diameter might be different, but reflects the size of internal carotid artery passing through the bony carotid canal. In this study, we aimed to identify the relationship between bony carotid canal diameter and clinical manifestation.
METHODS
146 consecutive patients diagnosed with moyamoya disease by brain imaging studies were included. We measured the diameter of a transverse portion of bony carotid canal on bone window of a brain computed tomography(CT) image. Patients were divided into two groups, ischemic or hemorrhagic stroke according to clinical manifestation. As a result, 115 patients were included. The Suzuki stage was used as criteria for disease progression.
RESULTS
Bony carotid canal diameter was 3.6 ± 0.5 (right) and 3.6 ± 0.4 (left) in the hemorrhagic stroke group, and 3.7 ± 0.4 (right) and 3.6 ± 0.4 (left) in the ischemic stroke group. The bony carotid canal diameter of the moyamoya vessels (3.6 mm) was smaller than the diameter of non-moyamoya vessels (3.8 mm), significantly (p= 0.042). However, there was no difference in the collateral patterns and clinical manifestation in a comparison of both groups.
CONCLUSIONS
In our study, there was no significant difference of clinical manifestations and collateral patterns depend on the bony carotid canal diameter in patients with moyamoya disease. These findings suggest that the clinical presentations of moyamoya disease are not related to the onset time of the disease.

Keyword

Moyamoya disease; Carotid canal; Stroke

MeSH Terms

Anterior Cerebral Artery
Brain
Carotid Artery, Internal
Constriction, Pathologic
Disease Progression
Humans
Middle Cerebral Artery
Moyamoya Disease*
Neuroimaging
Stroke

Figure

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  Figure 1. Measurement of bony carotid canal diameter. Bony carotid canal diameter was measured by transverse portion of bony carotid canal on bone window setting of brain CT (diameter of bidirectional arrow). CT; computed tomography.

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  Figure 2. Relations of Suzuki stages and bony carotid canal diameter. Bony carotid canal diameter was compared in each ischemic and hemorrhage group according to Suzuki criteria.

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  Figure 3. Relations of bony carotid canal size and collateral patterns. Bony carotid canal size was divided into two groups. Average of moyamoya disease vessel diameter (3.6 mm) was the standard of small and large groups. Each group showed different collateral patterns. BCC; bony carotid canal.

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  Figure 4. Relations of clinical manifestation and collateral patterns. Clinical manifestation was divided into two groups, ischemic and hemorrhagic stroke group. Each group showed different collateral patterns.

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