J Korean Soc Transplant.  2016 Jun;30(2):69-76. 10.4285/jkstn.2016.30.2.69.

Current Status of Solid Organ Xenotransplantation

Affiliations
  • 1Department of Surgery, Konkuk University School of Medicine, Seoul, Korea. ijyun@kuh.ac.kr

Abstract

Solid organ xenotransplantation using transgenic pig organs is proposed as an alternative method for allo-transplantation. To accomplish this, immunologic and non-immunologic barriers for xenotransplantation should be overcome, and experiments on pigs to non-human primates (NHP) are now ongoing for clinical application. Before the clinical experiment, public consensus about ethical decisions must be considered. The results of NHP experiments on solid organ xenotransplantation are improving, and it is expected that xeno-solid organs can be used as new organs for human patients in the future.

Keyword

Xenotransplantation; Solid organ transplantation; Transgenic pig
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