J Nutr Health.  2014 Feb;47(1):45-50.

Systematic review of the effect of dried ginger powder on improvement of nausea and vomiting associated with early pregnancy or motion sickness

Affiliations
  • 1Biofood CRO Co., Ltd., Seoul 120-160, Korea.
  • 2Biofood Network Center, Ewha Womans University, Seoul 120-750, Korea. orank@ewha.ac.kr
  • 3Department of Food Science and Technology, Seoul National University of Science and Technology, Seoul 139-743, Korea.
  • 4Department of Nutritional Science and Food Management, Ewha Womans University, Seoul 120-750, Korea.

Abstract

PURPOSE
Ginger (Zingiber officinale) has been widely used as an antiemetic agent. This systematic review was aimed at evaluation of the effect of dried ginger powder supplementation on improvement of nausea and vomiting associated with early pregnancy or motion sickness.
METHODS
We searched Pubmed, Cochrane, Science Direct, and KISS (Korean studies Information Service System) using keywords such as ginger or Zingiber officinale in combination with nausea, vomiting, motion sickness, or pregnancy, published in March 2013.
RESULTS
The strength of the evidence was evaluated on the selected 12 RCTs (randomized controlled trials). Eleven trials including 2,630 subjects showed that supplementation with dried ginger powder resulted in significant improvement of nausea or vomiting related to early pregnancy or motion sickness. Among the nine studies including 809 women in early pregnancy before 20 weeks of gestation, ginger supplementation was superior to placebo in five studies (n = 305), and as effective as positive control (vitamin B6 or dimenhydrinate) in four studies (n = 504). Ginger intake significantly reduced the episodes or severity of vomiting related to motion sickness compared to placebo or showed the same effect as several antiemetic drugs in two studies (n = 1,821).
CONCLUSION
Our findings added evidence indicating that ginger powder supplements might improve the symptoms of nausea or vomiting related to early pregnancy or motion sickness without significant adverse events.

Keyword

systematic review; Zingiber officinale; morning sickness; motion sickness
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