J Neurogastroenterol Motil.  2012 Apr;18(2):131-137.

Gastric Electrical Stimulation for Gastroparesis

Affiliations
  • 1Cedars Sinai Medical Center, Los Angeles, CA, USA. edy.soffer@cshs.org

Abstract

Gastric electrical stimulation (GES) for gastroparesis has been in use for more than a decade. Multiple publications, consisting almost entirely of open label single center studies, reported a beneficial effect on symptoms, quality of life and nutritional status. Some predictors of better response to GES have been lately identified, primarily diabetic etiology and nausea and vomiting as the predominant symptoms. However, individual response to GES remains difficult to predict. The mechanism of action of GES remains poorly understood. Stimulation parameters approved in clinical practice do not regulate gastric slow wave activity and have inconsistent effect on gastric emptying. Despite such limitations, gastric electrical stimulation remains a helpful intervention in some patients with severe gastroparesis who fail to respond to medical therapy.

Keyword

Electrical stimulation; Gastric emptying; Gastroparesis

MeSH Terms

Electric Stimulation
Gastric Emptying
Gastroparesis
Humans
Nausea
Nutritional Status
Quality of Life
Vomiting
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