J Menopausal Med.  2014 Apr;20(1):35-38.

Abdominal Wall Metastasis of Uterine Papillary Serous Carcinoma in a Post-Menopausal Woman: A Case Report

Affiliations
  • 1Department of Obstetrics and Gynecology, Dong-A University College of Medicine, Busan, Korea.
  • 2Department of Obstetrics and Gynecology, Inha University College of Medicine, Incheon, Korea. sohwang@inha.ac.kr

Abstract

Uterine papillary serous carcinoma (UPSC) is an aggressive form of endometrial cancer characterized by a high recurrence rate and poor prognosis. We report a case of a 58-year-old post-menopausal woman with an abdominal wall metastasis in stage IA UPSC. After surgical staging, she did not receive additional adjuvant therapy. An egg sized palpable mass developed in the right lower abdomen after 8 months. Both Abdominopelvic computed tomography (CT) and positron emission tomography (PET)-CT revealed a metastatic lesion in the abdominal wall. Hence, surgical excision was performed. The pathological findings showed metastatic UPSC with clear resection margin. After the diagnosis of UPSC metastasis in the abdominal wall, she received chemotherapy utilizing paclitaxel and carboplatin. After 3 years, no evidence of recurrence was found. Therefore, we suggest that even when UPSC is confined to the endometrium without lymph node metastasis and without lymphovascular invasion, chemotherapy should be considered as a postoperative adjuvant therapy.

Keyword

Abdominal wall; Postmenopause; Uterine papillary serous carcinoma

MeSH Terms

Abdomen
Abdominal Wall*
Carboplatin
Diagnosis
Drug Therapy
Endometrial Neoplasms
Endometrium
Female
Humans
Lymph Nodes
Middle Aged
Neoplasm Metastasis*
Ovum
Paclitaxel
Positron-Emission Tomography
Postmenopause
Prognosis
Recurrence
Carboplatin
Paclitaxel

Figure

  • Fig. 1 Papillary serous adenocarcinoma, a primary lesion in the uterus, shows no myometrial invasion (H&E × 400).

  • Fig. 2 Abdominopelvic computed tomography shows a 4.4 × 4.1 cm sized low attenuated septated cystic mass in the right lower quadrant abdominal wall (arrow).

  • Fig. 3 Positron emission tomography-computed tomography shows abnormal hypermetabolic lesion in the right lower quadrant abdomen wall.

  • Fig. 4 Section of the excised mass from the abdominal wall discloses metastatic carcinoma with features of serous adenocarcinoma (H&E ×400).


Reference

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