J Korean Acad Rehabil Med.
2007 Apr;31(2):238-242.
The Effect of Levodopa on Akinetic Mutism in Bilateral Anterior Cerebral Artery Infarction: A case report
- Affiliations
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- 1Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Korea. presider@hanmail.net
Abstract
- Akinetic mutism is a clinical syndrome in which the patient is unable to speak (mutism) or move (akinesia). Various brain lesions can induce akinetic mutism. We attended a 71-year-old woman who presented with akinetic mutism caused by bilateral anterior cerebral artery infarction. The patient improved after the administration of levodopa com-bined with carbidopa, in response to visual and verbal stimuli. Increased verbal output and spontaneous motor activities were also noted. Levodopa may be helpful to the treatment of akinetic mutism.
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