Tuberc Respir Dis.  2014 Jul;77(1):38-41.

A Case of Lung Carcinoma with Rhabdoid Phenotype Mimicking an Aspergilloma in Patient with Recurrent Hemoptysis

• Kim MW
• Rew SJ
• Eun SJ
• Lee US
• Park CW
• Jeong JP
• Ko YC

Abstract

Malignant rhabdoid tumor was first discovered in the kidney, and rhabdoid tumor of the lung was first reported in 1995. These were included as the variants of large-cell carcinoma, according to the 1999 World Health Organization classification of lung tumors. The rhabdoid tumor of the lung exhibits aggressive biological behavior and has a poor prognosis, and only a few reports of this tumor exist. We report a case of lung carcinoma with a rhabdoid phenotype, initially misdiagnosed as an aspergilloma, in a 48-year-old man who presented with recurrent hemoptysis. The chest computed tomography scans showed a huge consolidative lesion with an air crescent sign in the left upper lung and no contrast-enhancing lesion. An aspergilloma was diagnosed by the radiologist. However, after surgical excision and pathological examination, rhabdoid carcinoma was diagnosed. A surgical resection helps to make it possible to pathologically distinguish a malignancy from an aspergilloma.

Keyword

Rhabdoid Tumor; Hemoptysis; Aspergillosis

MeSH Terms

Aspergillosis
Classification
Hemoptysis*
Humans
Kidney
Lung*
Middle Aged
Phenotype*
Prognosis
Rhabdoid Tumor
Thorax
World Health Organization

Figure

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  Figure 1 Computed tomography scan of the chest shows a huge (8.3-cm extent) consolidative lesion with air crescent sign (A), internal high attenuation, and bubble lucency in the left apical lung (B).

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  Figure 2 (A) The patient underwent surgical operation of the left upper lobectomy and decortication. (B) There was a 20×12×8-cm-sized mass containing 8×7-cm-sized cavitary lesion with extensive central necrosis.

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  Figure 3 Histopathologic examination showed large nucleus with atypism (arrows) and focally eccentric eosinophilic cytoplasm (H&E stain, ×200).

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