Tuberc Respir Dis.  2013 Aug;75(2):75-78.

Community-Acquired Necrotizing Pneumonia Caused by ST72-SCCmec Type IV-Methicillin-Resistant Staphylococcus aureus in Korea

• Hwang JW
• Joo EJ
• Ha JM
• Lee W
• Kim E
• Yune S
• Chung DR
• Jeon K

Abstract

Methcillin-resistant Staphylococcus aureus (MRSA) has emerged as an important cause of community-acquired infections, which has been recently designated as community-associated (CA) MRSA. Panton-Valentine leukocidin (PVL)-negative multilocus sequence type 72 (ST72)-staphylococcal cassette chromosome mec (SCCmec) type IV has been reported as the predominat CA-MRSA strain in Korea and is commonly associated with skin and soft tissue infections in addition to healthcare-associated pneumonia. However, community-acquired pneumonia (CAP) for this strain has not yet been reported. We hereby report two cases of CAP caused by PVL-negative ST72-SCCmec type IV strain in patients who had no risk factors for MRSA acquisition. While CA-MRSA infections are not yet prevalent in Korea, our cases suggest that CA-MRSA should be considered in cases of severe CAP, especially for cases associated with necrotizing pneumonia.

Keyword

Methicillin-Resistant Staphylococcus aureus; Pneumonia; Community-Acquired Infections; Korea

MeSH Terms

Bacterial Toxins
Community-Acquired Infections
Exotoxins
Humans
Korea
Leukocidins
Methicillin-Resistant Staphylococcus aureus
Pneumonia
Risk Factors
Skin
Soft Tissue Infections
Sprains and Strains
Staphylococcus
Staphylococcus aureus
Bacterial Toxins
Exotoxins
Leukocidins

Figure

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  Figure 1 Chest computed tomography of a 66-year-old man with community-associated methicillin-resistant Staphylococcus aureus pneumonia shows consolidation and ground-glass opacity with cavitation in the lower left lobe.

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  Figure 2 Chest computed tomography of a 57-year-old woman with community-associated methicillin-resistant Staphylococcus aureus pneumonia shows multiple patchy consolidations in both lower lobes and the middle right lobe.

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