Tuberc Respir Dis.  2011 Dec;71(6):445-449.

Asymptomatic Solitary Renal Metastasis Detected during Surveillance after Curative Surgery for Squamous Cell Carcinoma of Lung

• Song SH
• Jun YJ
• Paik SS
• Kwak HJ
• Kim SH
• Kim TH
• Sohn JW
• Shin DH
• Park SS
• Yoon HJ

Abstract

Non small cell lung cancer (NSCLC) frequently metastasizes to brain, bone, liver, and adrenal glands. While an autopsy of NSCLC reveals some cases of metastasis to the kidney, clinical detection of renal metastases is extremely rare. Furthermore, metastases to the kidney usually present as multifocal or bilateral lesions and solitary renal metastases are usually suspected to be renal cell carcinoma. We now report a case of asymptomatic solitary renal metastasis from a primary squamous cell carcinoma, which was detected by routine surveillance with abdominal CT after curative surgery.

Keyword

Lung Neoplasms; Carcinoma, Squamous Cell; Neoplasm Metastasis, Kidney

MeSH Terms

Adrenal Glands
Autopsy
Brain
Carcinoma, Renal Cell
Carcinoma, Squamous Cell
Kidney
Liver
Lung
Lung Neoplasms
Neoplasm Metastasis
Small Cell Lung Carcinoma

Figure

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  Figure 1 Computed tomographic scan of the chest shows a tumor in the right upper lobe with invasion and compression of the right main bronchus 2cm or more from the carina (white arrow).

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  Figure 2 Computed tomographic scan of the abdomen shows a cystic mass with peripheral enhancement in the right kidney (white arrow).

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  Figure 3 The metastatic renal tumor shows a poorly differentiated carcinoma with squamoid differentiation (A, hematoxylin and eosin, ×200). The tumor cells are positive for p63 (B, Papanicolaou stain, ×100) and cytokeratin 7 (C, Papanicolaou stain, ×100) immunostainings.

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  Figure 4 The tumor shows squamous cell carcinoma with well to moderate differentiation (A, hematoxylin and eosin, ×200). The tumor cells are positive for p63 (B, Papanicolaou stain, ×100) and cytokeratin 7 (C, Papanicolaou stain, ×200) immunostainings.

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