Vasc Spec Int.
2014 Dec;30(4):125-132. 10.5758/vsi.2014.30.4.125.
Prevalence and Risk Factors for the Peripheral Neuropathy in Patients with Peripheral Arterial Occlusive Disease
- Affiliations
-
- 1Department of Surgery, Seoul Medical Center, Seoul, Korea. kblee0925@me.com
- 2Department of Rehabilitation Medicine, Seoul Medical Center, Seoul, Korea.
- 3Department of Radiology, Seoul Medical Center, Seoul, Korea.
- KMID: 2319497
- DOI: http://doi.org/10.5758/vsi.2014.30.4.125
Abstract
- PURPOSE
Peripheral neuropathy (PN) is known as a major contributor of the worsening of ischemic symptoms and the foot ulceration in patients with peripheral arterial occlusive disease (PAOD). However, there are few studies reporting the prevalence and risk factors for PN in PAOD. This study aimed to evaluate these issues for PN and to establish the importance of screening as additional treatment target for PN in PAOD.
MATERIALS AND METHODS
A total of 52 limbs with PAOD were enrolled from January 2011 to December 2012. PN was divided into radiculopathy, ischemic PN (IPN), and diabetic PN (DPN), based on electromyographic findings. We investigated the prevalence of overall PN and subtypes of PN and then analyzed the risk factors.
RESULTS
The prevalence of overall PN in PAOD was 43 of 52 limbs (82.7%). In terms of subtypes of PN, the prevalence rate of radiculopathy and IPN was 30.8% and 23.1%, respectively. DPN showed in 22 limbs (73.3%) among 30 diabetic limbs. There was no significant correlation between each type of PN and ischemic symptoms. Our analysis showed that coronary artery disease (CAD) was a significant risk factor (P=0.01) for IPN, however, did not identify any significant risk factors for DPN.
CONCLUSION
This present study indicated that most patients with PAOD had PN and CAD was a risk factor for IPN. In particular, PAOD with diabetes represented a higher prevalence for DPN. Our study suggests that PN should be evaluated and considered as another treatment target in patients with PAOD.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Ischemic Monomelic Neuropathy and Myopathy as a Complication of Peripheral Arterial Occlusive Disease
- Pathogenesis of the Diabetic Foot Disease
- Peripheral Arterial Occlusion in Young Adult: 2 cases
- Premature Peripheral Arterial Disease with the 5th Toe Necrotizing Lesion after Workout: A Case Report
- Noninvasive Diagnostic Modalities for Peripheral Arterial Occlusive Disease
