Urogenit Tract Infect.  2016 Apr;11(1):36-38. 10.14777/uti.2016.11.1.36.

Tuberculosis of the Glans Penis Presenting as Glans Gangrene

Affiliations
  • 1Department of Urology, Catholic University of Daegu School of Medicine, Daegu, Korea. jspark@cu.ac.kr

Abstract

Tuberculosis of the glans penis is rare. The clinical features of tuberculosis of the glans penis include the appearance of a superficial ulcer of the glans. We recently experienced a case of tuberculosis of the glans penis presenting as an ulcer, which progressed to glans necrosis. A 46-year-old man presented at our institution with painful ulcerative penile lesions. Initial pathological findings of the ulcers showed non-granulomatous inflammatory changes. He was treated with antibiotics and anti-inflammatory drugs for 6 months, and during that time, his glans ulcers progressed to glans gangrene. A partial glansectomy showed multiple epithelioid granulomas with central caseous necrosis, which was compatible with the findings of tuberculosis. The patient received anti-tuberculosis chemotherapy. The current case is reported to alert physicians to consider the possibility of tuberculosis when evaluating unusual penile glans lesions.

Keyword

Glans penis; Tuberculosis; Ulcer; Gangrene

MeSH Terms

Anti-Bacterial Agents
Drug Therapy
Gangrene*
Granuloma
Humans
Male
Middle Aged
Necrosis
Penis*
Tuberculosis*
Ulcer
Anti-Bacterial Agents

Figure

  • Fig. 1. His glans shows two painful adjacent 12×8 mm sized ulcers with peripheral dusky areas.

  • Fig. 2. His glans lesions progressed to glans gangrene.

  • Fig. 3. (A) Chronic granulomatous inflammatory lesions in epithelial cells with central caseation necrosis (arrow; H&E stain, ×100). (B) Multinucleated giant Langerhan's cells (arrowhead; H&E stain, ×400).


Reference

References

1. Lee JY, Park HY, Park SY, Lee SW, Moon HS, Kim YT, et al. Clinical characteristics of genitourinary tuberculosis during a recent 10-year period in our center. Korean J Urol. 2011; 52:200–5.
2. Jacob JT, Nguyen TM, Ray SM. Male genital tuberculosis. Lancet Infect Dis. 2008; 8:335–42.
Article
3. Yonemura S, Fujikawa S, Su JS, Ohnishi T, Arima K, Sugimura Y. Tuberculid of the penis with a scab on the nodule. Int J Urol. 2004; 11:931–3.
Article
4. Jaisankar TJ, Garg BR, Reddy BS, Riba B, Ramarao AP. Penile lupus vulgaris. Int J Dermatol. 1994; 33:272–4.
Article
5. Kar JK, Kar M. Primary tuberculosis of the glans penis. J Assoc Physicians India. 2012; 60:52–3.
6. Sah SP, AshokRaj G, Joshi A. Primary tuberculosis of the glans penis. Australas J Dermatol. 1999; 40:106–7.
Article
7. Richard BO, William DJ, Timothy GB. Disease of the skin. Philadelphia: WB Saunders;2000.
8. Yanagihara H. Risk of tuberculosis infection among care workers during an outbreak of tuberculosis at a care facility for the elderly. Kekkaku. 2014; 89:631–6.
9. Brisson-Noel A, Gicquel B, Lecossier D, Levy-Frebault V, Nassif X, Hance AJ. Rapid diagnosis of tuberculosis by amplification of mycobacterial DNA in clinical samples. Lancet. 1989; 2:1069–71.
Full Text Links
  • UTI
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr