Psychiatry Investig.  2013 Dec;10(4):428-431.

A Case with Neutropenia Related with the Use of Various Atypical Antipsychotics

Affiliations
  • 1Department of Psychiatry, College of Medicine, Dankook University, Cheonan, Republic of Korea.
  • 2Department of Psychiatry, Chonbuk National University Medical School, Jeonju, Republic of Korea. ptaewon@jbnu.ac.kr
  • 3Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Republic of Korea.

Abstract

Herein, we report here a case of a 21-year-old patient with a conduct disorder, who had neutropenia associated with treatment with 4 different antipsychotics (olanzapine, quetiapine, risperidone, and aripiprazole) on a sequential basis. This case supports the hypothesis that patients who developed antipsychotic-induced neutropenia on one medication are more likely to develop neutropenia when taking other antipsychotics. Based on this finding, we may suggest that the number of white blood cell and neutrophil counts in patients with a history of antipsychotic-induced neutropenia needs to be carefully monitored during antipsychotic treatment.

Keyword

Multiple atypical antipsychotics; Neutropenia

MeSH Terms

Antipsychotic Agents*
Conduct Disorder
Humans
Leukocytes
Neutropenia*
Neutrophils
Risperidone
Young Adult
Quetiapine Fumarate
Antipsychotic Agents
Risperidone
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