Psychiatry Investig.  2013 Mar;10(1):92-94.

A Case of Clozapine Induced Acute Renal Failure

Affiliations
  • 1Department of Psychiatry & Behavioral Sciences, Ajou University School of Medicine, Suwon, Republic of Korea. jsnoh@ajou.ac.kr

Abstract

There have been a few case reports that clozapine, an atypical antipsychotic, caused acute renal failure of interstitial type. Here we report a case of a 38-year-old Korean male patient with treatment-resistant bipolar I disorder who developed acute renal failure after the initiation of treatment with clozapine. We describe the clinical and laboratory findings of the case and discuss the measures for early detection of this life threating condition. Within our knowledge, this is the first report of clozapine-induced acute renal failure in South Korea.

Keyword

Clozapine; Acute renal failure; Interstitial nephritis; Bipolar I disorder

MeSH Terms

Acute Kidney Injury
Clozapine
Humans
Male
Nephritis, Interstitial
Republic of Korea
Clozapine
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