Psychiatry Investig.  2011 Mar;8(1):1-8.

The Clinical Research Center for Depression Study: Baseline Characteristics of a Korean Long-Term Hospital-Based Observational Collaborative Prospective Cohort Study

Affiliations
  • 1Department of Psychiatry, The Catholic University of Korea School of Medicine, Seoul, Korea. tyjun@catholic.ac.kr
  • 2Clinical Research Center for Depression, Seoul, Korea.
  • 3Department of Preventive Medicine, The Catholic University of Korea School of Medicine, Seoul, Korea.
  • 4Department of Psychiatry, Keimyung University School of Medicine, Daegu, Korea.
  • 5Department of Psychiatry, College of Medicine, Korea University, Seoul, Korea.
  • 6Department of Psychiatry, Chonnam National University Medical School, Gwangju, Korea.

Abstract


OBJECTIVE
The Clinical Research Center for Depression (CRESCEND) study is a 9-year observational collaborative prospective cohort study for the clinical outcomes in participants with depressive disorders in Korea. In this study, we examined the baseline characteristics of the depressive participants as the hospital-based cohort.
METHODS
Participants were assessed using various instruments including the Clinical Global Impression scale, 17-item Hamilton Depression Rating Scale (HDRS-17), Hamilton Anxiety Rating Scale, Brief Psychiatric Rating Scale, Social and Occupational Functioning Assessment Scale, Beck Depression Inventory-Second Edition, Scale for Suicide Ideation, and World Health Organization Quality of Life assessment instruments-abbreviated version. Also, personal histories of medical and psychiatric illnesses and the range of socio-epidemiologic and clinical data were collected from each participant.
RESULTS
One thousand one hundred eighty three participants were recruited from 18 hospitals. The mean age of the participants was 47.9+/-15.9 year-old, 74.4% were female, 82.9% had been diagnosed of major depressive disorder, 40.9% were experiencing their first depressive episode, and 21.4% had a past history of suicide attempts. The majority (85.3%) of the participants were moderately to severely ill. The average HDRS-17 was 19.8+/-6.1. Significant gender differences at baseline were shown in age, education, marriage, employment, religion, and first depressive episode.
CONCLUSION
The baseline findings in the CRESCEND study showed some different characteristics of depression in Korea, suggesting a possibility of ethnic and cultural factors in depression.

Keyword

Depression; Hospital-based; Longitudinal; Observational; Prospective

MeSH Terms

Anxiety
Brief Psychiatric Rating Scale
Cohort Studies
Depression
Depressive Disorder
Depressive Disorder, Major
Employment
Female
Humans
Korea
Marriage
Prospective Studies
Quality of Life
Suicide
World Health Organization
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