Pediatr Allergy Respir Dis.  2012 Mar;22(1):4-20.

Guidelines for the Oral Food Challenges in Children

Affiliations
  • 1Department of Pediatrics, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
  • 2Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
  • 3Department of Pediatrics, Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.
  • 4Department of Pediatrics, Inha University School of Medicine, Incheon, Korea.
  • 5Department of Pediatrics, The Catholic University of Korea School of Medicine, Seoul, Korea.
  • 6Department of Pediatrics, Konkuk University School of Medicine, Seoul, Korea.
  • 7Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
  • 8Department of Pediatrics, Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea. bypyun@schmc.ac.kr
  • 9Atopy Clinic, Seoul Medical Center, Seoul, Korea.
  • 10Department of Pediatrics, Ajou University School of Medicine, Suwon, Korea.

Abstract

Oral food challenge is a definitive diagnostic test for immediate and occasionally delayed adverse reaction to foods. The gold standard for diagnosing food allergy is still the double-blind, placebo-controlled food challenge, but it is time-consuming, expensive and troublesome for physician and patients. Open oral food challenge controlled by trained personnel is useful and sufficient methods when concern of bias is low. We aimed to provide a practical guideline for oral food challenge in children for the diagnosis of suspected food allergy or the evaluation of food tolerance. We considered reasons, types, indications, contraindications, risks, benefits, detailed methods, practical performance, interpretations of test results, and treatments for the adverse reactions of oral food challenge.

Keyword

Oral food challenge; Food allergy
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