Korean J Urol.  2009 Dec;50(12):1265-1268.

Extramammary Paget's Disease Involving the Scrotum and Umbilicus

• Park S
• Lee SK
• Ji YH
• Kim J
• Kim YM
• Moon KH

Abstract

Extramammary Paget's disease (EMPD) is a rare intraepithelial adenocarcinoma. To date, about 200 cases of EMPD have been reported since the first report in 1889. There has been only one case of EMPD involving the umbilicus, in a patient with prostatic carcinoma. This is the first report of EMPD occurring concurrently in the scrotum and umbilicus. The patient had recurrent, eczematous, and pruritic lesions of the left scrotum and umbilicus 2 years previously. Biopsy and surgical resection were performed and EMPD was diagnosed. There was no evidence of recurrence at 34 months after surgery.

Keyword

Extramammary Paget's disease; Scrotum; Umbilicus

MeSH Terms

Adenocarcinoma
Biopsy
Humans
Paget Disease, Extramammary
Recurrence
Scrotum
Umbilicus

Figure

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  Fig. 1 Preoperative photograph showing extramammary Paget's disease manifesting as scaly, dark red-brown plaques with well-defined borders on the umbilicus (about 1×1 cm sized).

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  Fig. 2 Photomicrography showing proliferation of abundant pale Paget's cells with scattered atypical nuclei in the epidermis (H&E, reduced from ×100).

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  Fig. 3 The lower layer of Paget's cells in the epidermis formed gland-like aggregates (H&E, reduced from ×400).

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  Fig. 4 Postoperative photographs at 4 months after surgery showing complete healing of the lesions on the umbilicus.

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