Nutr Res Pract.  2013 Aug;7(4):256-261.

Effects of perilla oil on plasma concentrations of cardioprotective (n-3) fatty acids and lipid profiles in mice

• Chung KH
• Hwang HJ
• Shin KO
• Jeon WM
• Choi KS

Abstract

The aim of this study was to examine the effects of perilla oil as well as several vegetable oils, including flaxseed oil, canola oil, and rice bran oil on plasma levels of cardioprotective (n-3) polyunsaturated fatty acids in mice by feeding each vegetable oil for a period of eight weeks. Concentrations of docosapentaenoic acid (DHA) and eicosapentaenoic acid (EPA), fish-based (n-3) polyunsaturated fatty acids, showed an increase in the plasma of mice fed perilla and flaxseed oils compared to those of mice in the control group (P < 0.05), whereas rice bran and canola oils did not alter plasma DPA and EPA concentrations. Arachidonic acid concentration was increased by feeding rice bran oil (P < 0.05), but not canola, flaxseed, or perilla oil. In addition, oleic acid, linoleic acid, and docosahexaenoic acid concentrations were altered by feeding dietary rice bran, canola, perilla, and flaxseed oils. Findings of this study showed that perilla oil, similar to flaxseed oil, is cardioprotective and could be used as an alternative to fish oil or even flaxseed oil in animal models.

Keyword

Perilla oil; flaxseed oil; (n-3) polyunsaturated fatty acids; DPA; EPA

MeSH Terms

alpha-Linolenic Acid
Animals
Arachidonic Acid
Eicosapentaenoic Acid
Fatty Acids
Fatty Acids, Monounsaturated
Fatty Acids, Unsaturated
Flax
Linoleic Acid
Linseed Oil
Mice
Models, Animal
Oils
Oleic Acid
Perilla
Plant Oils
Plasma
Vegetables
Arachidonic Acid
Eicosapentaenoic Acid
Fatty Acids
Fatty Acids, Monounsaturated
Fatty Acids, Unsaturated
Linoleic Acid
Linseed Oil
Oils
Oleic Acid
Plant Oils
alpha-Linolenic Acid