Nutr Res Pract.  2011 Oct;5(5):429-434.

Effects of a Rubus coreanus Miquel supplement on plasma antioxidant capacity in healthy Korean men

Affiliations
  • 1Department of Home Economics Education, Chung-Ang University, Heuksuk-dong, Dongjak-gu, Seoul 156-756, Korea. jjhkim@cau.ac.kr
  • 2Department of Food Science & Technology, Chung-Ang University, Gyeonggi 456-756, Korea.
  • 3College of Pharmacy, Chung-Ang University, Seoul 156-756, Korea.
  • 4Functional Food & Nutrition Division, Rural Development Administration, Gyeonggi 441-853, Korea.

Abstract

Korean raspberry, Rubus coreanus Miquel (RCM), contains high concentrations of phenolic compounds, which prevent oxidative stress. To determine the effect of RCM on antioxidant capacity in humans, we assessed in vivo lipid oxidation and antioxidant enzyme activities from plasma in 15 healthy men. The subjects ingested 30 g of freeze-dried RCM daily for 4 weeks. Blood was taken at baseline and at the end of the study to determine blood lipid profiles, fasting plasma glucose, liver function, lipid peroxidation, and antioxidant enzyme activities. RCM supplementation had no effect on blood lipid or fasting plasma glucose concentrations but decreased alkaline phosphatase activity. RCM supplementation increased glutathione peroxidase activities (P < 0.05) but had no effect on lipid peroxidation. These results suggest that short-term RCM supplementation may offer health benefits by enhancing antioxidant capacity in a healthy population.

Keyword

Rubus coreanus Miquel; antioxidant; lipid peroxidation; glutathione peroxidase

MeSH Terms

Alkaline Phosphatase
Fasting
Glucose
Glutathione Peroxidase
Humans
Insurance Benefits
Lipid Peroxidation
Liver
Male
Oxidative Stress
Phenol
Plasma
Alkaline Phosphatase
Glucose
Glutathione Peroxidase
Phenol

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