Nucl Med Mol Imaging.  2009 Aug;43(4):361-362.

A Neurofibroma Confused with Sarcomatous Transformation on F-18 FDG PET/CT in Neurofibromatosis-1

Affiliations
  • 1Department of Nuclear Medicine, Wonkwang University College of Medicine, Iksan, Korea. nmbach@wonkwang.ac.kr
  • 2Department of Plastic and Reconstructive Surgery, Wonkwang University College of Medicine, Iksan, Korea.
  • 3Department of Physical Medicine and Rehabilitation, Wonkwang University College of Medicine, Iksan, Korea.
  • 4Department of Pathology, Wonkwang University College of Medicine, Iksan, Korea.
  • 5Department of Urology, Wonkwang University College of Medicine, Iksan, Korea.
  • 6Department of Institute of Wonkwang Medical Science, Wonkwang University College of Medicine, Iksan, Korea.

Abstract

We present a patient with high 18F-fluorodeoxyglucose (FDG) uptake detected in a neurofibroma that was confused with sarcomatous transformation on a positron emission tomography/computed tomography (PET/CT) scan. A 39-year-old male patient with a 20-year history of neurofibromatosis-1 (NF-1) performed FDG PET/CT scan for the evaluation of lesions with sarcomatous transformation. The FDG PET/CT images demonstrated varying degrees of increased FDG uptake in the multiple nodules throughout whole body. The left pelvic mass with the highest FDG uptake had a maximum standardized uptake values (maxSUV) 5.0 and surgical resection was performed. Histological analysis confirmed the presence of a benign neurofibroma infiltrated with inflammatory cells.

Keyword

PET/CT; F-18 fluorodeoxyglucose; neurofibromatosis

MeSH Terms

Adult
Electrons
Humans
Male
Neurofibroma
Neurofibromatoses
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