Nucl Med Mol Imaging.  2007 Apr;41(2):97-101.

Nuclear Imaging in Epilepsy

Affiliations
  • 1Department of Nuclear Medicine, Yeungnam University Hospital, Daegu, Korea. cka52@yumail.ac.kr

Abstract

Correct localization of epileptogenic zone is important for the successful epilepsy surgery. Both ictal perfusion single photon emission computed tomography (SPECT) and interictal F-18 fluorodeoxyglucose positron emission tomography (FDG-PET) can provide useful information in the presurgical localization of intractable partial epilepsy. These imaging modalities have excellent diagnostic sensitivity in medial temporal lobe epilepsy and provide good presurgical information in neocortical epilepsy. Also provide functional information about cellular functions to better understand the neurobiology of epilepsy and to better define the ictal onset zone, symptomatogenic zone, propagation pathways, functional deficit zone and surround inhibition zones. Multimodality imaging and developments in analysis methods of ictal perfusion SPECT and new PET ligand other than FDG help to better define the localization.

Keyword

Epilepsy; SPECT; PET

MeSH Terms

Epilepsies, Partial
Epilepsy*
Epilepsy, Temporal Lobe
Neurobiology
Perfusion
Positron-Emission Tomography
Tomography, Emission-Computed, Single-Photon
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