Mycobiology.  2015 Sep;43(3):333-338. 10.5941/MYCO.2015.43.3.333.

Antifungal Substances from Streptomyces sp. A3265 Antagonistic to Plant Pathogenic Fungi

Affiliations
  • 1Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Chonbuk National University, Iksan 54596, Korea. bsyun@jbnu.ac.kr

Abstract

In a previous study, we identified a Streptomyces sp., A3265, as exhibiting potent antifungal activity against various plant pathogenic fungi, including Botrytis cinerea, Colletotrichum gloeosporioides, and Rhizoctonia solani. This strain also exhibited a biocontrolling effect against ginseng root rot and damping-off disease, common diseases of ginseng and other crops. In this study, we isolated two antifungal substances responsible for this biocontrolling effect via Diaion HP-20 and Sephadex LH-20 column chromatography, medium pressure liquid chromatography, and high-performance liquid chromatography. These compounds were identified as guanidylfungin A and methyl guanidylfungin A by spectroscopic methods. These compounds exhibited potent antimicrobial activity against various plant pathogenic fungi as well as against bacteria.

Keyword

Biocontrol agent; Damping-off; Guanidylfungin; Streptomyces sp. A3265

MeSH Terms

Bacteria
Botrytis
Chromatography
Chromatography, Liquid
Colletotrichum
Fungi*
Panax
Plants*
Rhizoctonia
Streptomyces*
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