Mycobiology.  2003 Jun;31(2):99-104.

In vitro Evaluation of Antidermatophytic Activity of Egyptian Bee Propolis in Combination with Plant Essential Oils in Sheep Hoof Plate: An Experimental Model

• Mahmoud YA

Abstract

Bee propolis ethanolic extract with some plant essential oils was investigated for its antidermatophytic properties. The tested plant essential oils included jasmine, clove, lemon, Arabian jasmine, mint, rosa, olive and basil. The antidermatophytic activity has been compared to Naftifine-HCl and Clotrimazole used for dermatophyte treatment. Experimental model has been tested using sheep hoof plate for the in vitro tests to stimulate human nails. Mint, clove and basil with 4 mg/ml of bee propolis have a comparable efficacy to those of Naftifine-HCl and Clotrimazole. There is a great necessity for new effective low price and safe antidermatophyte agents to avoid recurrent infection. Propolis synergistic could be of great importance with essential oils of plants in dermatophyte therapy.

Keyword

Antifungal drugs; Bee propolis; Dermatophytes; Plant essential oils

MeSH Terms

Animals
Arthrodermataceae
Bees*
Clotrimazole
Ethanol
Syzygium
Hoof and Claw*
Humans
Jasminum
Mentha
Models, Theoretical*
Ocimum basilicum
Oils, Volatile*
Olea
Plants*
Propolis*
Rosa
Sheep*
Clotrimazole
Ethanol
Oils, Volatile
Propolis