Kosin Med J.  2013 Jun;28(1):1-6. 10.7180/kmj.2013.28.1.1.

The Up-to-date Informations of Progesterone Supplementation for Prevention of Preterm Birth

Affiliations
  • 1Department of Obstetrics and Gynecology, College of Medicine, Inje University, Haeundae Paik Hospital, Busan, Korea. lory1202@naver.com

Abstract

Preterm birth (PTB) remains a major cause of neonatal mortality and morbidity, despite improvements in tocolytic treatment and neonatal care. Progesterone (17a-hydroxyprogesterone) produced naturally or synthetically can prevent PTB when applied vaginally and orally. Progesterone use may be a safe and cost-effective option in cases of singleton pregnancy with prior PTB, asymptomatically short cervix and arrested preterm labor.

Keyword

Cervical length; Preterm birth; Preterm labor; Progesterone

MeSH Terms

Cervix Uteri
Female
Humans
Infant
Infant Mortality
Obstetric Labor, Premature
Pregnancy
Premature Birth
Progesterone
Tocolysis
Progesterone

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