Korean J Vasc Endovasc Surg.  2012 Aug;28(3):133-141.

Identification of Prognostic Factors for In-Hospital Mortality in Acute Mesenteric Ischemia

Affiliations
  • 1Department of Surgery, Gyeongsang National University, Post-graduate School of Medicine, Jinju, Korea. orangejulia@naver.com

Abstract

PURPOSE
The purpose of this study was to determine the prognostic factors and risk scorings that could have an impact on the in-hospital mortality of acute mesenteric ischemia (AMI).
METHODS
Forty consecutive patients received an operation due to AMI between January 2001 and June 2009. The hospital medical charts and clinical records were retrospectively reviewed. Clinical features, laboratory findings, operative findings, surgical procedure, and prognostic scoring system were collected and assessed as possible the prognostic factors for in-hospital mortality.
RESULTS
The overall hospital mortality rate was 32.5% (13/40). In a univariate analysis, significant predictors of in-hospital mortality were decreased mentality (P=0.029), shock at admission (P=0.006), symptom duration (P=0.011), blood urea nitrogen (P=0.029), serum creatinine (P<0.001), glucose (P=0.004), total bilirubin (P=0.044), aspartate aminotransferase (P=0.001), lipase (P=0.039), pH (P=0.014), bicarbonate (P=0.027), prothrombin time-international normalized ratio (P=0.006), activated partial thromboplastin time (P=0.004), length of remnant bowel (P=0.008), postoperative inotropics (P=0.007), Acute Physiology and Chronic Health Evaluation II (P=0.009), and American Society of Anesthesiologists (ASA) grading (P=0.005). In a multivariate analysis, the variables hyperglycemia (P=0.013) and higher ASA (>II) (P=0.02) were identified as independent prognostic factors of in-hospital mortality.
CONCLUSION
In conclusion, the prognostic factors in AMI who have hyperglycemia (>200 mg/dL) and high ASA grading (>II) are truly associated with very high in-hospital mortality.

Keyword

Mesenteric vascular disease; Ischemia; Hospital mortality; Prognosis

MeSH Terms

APACHE
Aspartate Aminotransferases
Bilirubin
Blood Urea Nitrogen
Creatinine
Glucose
Hospital Mortality
Humans
Hydrogen-Ion Concentration
Hyperglycemia
Ischemia
Lipase
Multivariate Analysis
Partial Thromboplastin Time
Prognosis
Prothrombin
Retrospective Studies
Shock
Vascular Diseases
Aspartate Aminotransferases
Bilirubin
Creatinine
Glucose
Ischemia
Lipase
Prothrombin
Vascular Diseases
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