Korean J Gastroenterol.  2016 Jun;67(6):327-331. 10.4166/kjg.2016.67.6.327.

A Case of Pylephlebitis with Pseudomonas aeruginosa Sepsis and Liver Abscess Secondary to Diverticulitis

Affiliations
  • 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • 2Department of Internal Medicine, Cheongju St. Mary's Hospital, Cheongju, Korea. isle2001@gmail.com

Abstract

Pylephlebitis, or suppurative thrombophlebitis of the portal venous system, is a rare condition occurring secondary to abdominal infections such as diverticulitis. Pylephlebitis can be diagnosed via ultrasonography or CT scan, and is characterized by the presence of a thrombus in the portal vein and bacteremia. However, the diagnosis may be delayed due to the vague nature of the clinical symptoms, causing morbidity and mortality due to pylephlebitis to remain high. Early diagnosis and immediate antibiotic therapy are important for favorable prognosis. Therefore, pylephlebitis should be considered in the differential diagnosis for cases of nonspecific abdominal pain and fever. We report a case of pylephlebitis secondary to diverticulitis, associated with Pseudomonas aeruginosa sepsis. Such cases have not been widely reported.

Keyword

Thrombophlebitis; Diverticulitis; Sepsis; Liver abscess

MeSH Terms

Abdominal Pain
Bacteremia
Diagnosis
Diagnosis, Differential
Diverticulitis*
Early Diagnosis
Fever
Liver Abscess*
Liver*
Mortality
Portal Vein
Prognosis
Pseudomonas aeruginosa*
Pseudomonas*
Sepsis*
Thrombophlebitis
Thrombosis
Tomography, X-Ray Computed
Ultrasonography

Figure

  • Fig. 1. (A) Contrastenhanced abdominal and pelvic CT scans taken at admission. Low attenuation thrombi are visible in the superior mesenteric vein (white arrow). There is diffuse thickening of the cecum and ascending colon walls, associated with inflammation in the diverticula and pericolic fat. Diverticulitis can be seen at the black arrow and an ill-defined low density lesion is in the right liver parenchyma (arrowhead). (B) Low attenuation thrombi are visible in the right portal vein (white arrow).

  • Fig. 2. (A) Abdominal and pelvic CT scans, seven days after admission. Multiple thrombi are visible in the ileocolic vein and in the superior mesenteric vein (white arrows). The intensity of the inflammation in the cecum and the ascending colon has increased (black arrow), while the size of the low-density lesion in the right liver parenchyma has decreased (arrowhead). (B) Multiple thrombi are visible in the right portal vein (white arrow).

  • Fig. 3. Colonoscopic findings, 14 days after admission. Multiple diverticuli with erythematous mucosal changes around appendiceal orifice (white arrow) and adjacent mucosal erosions are visible in the cecum.

  • Fig. 4. (A) Abdominal and pelvic CT scans, 28 days after discharge. The CT scans show no significant change in the right portal vein thrombi (white arrow). (B) Some resolution of thrombosis in the superior mesenteric vein was noted (white arrow). (C) There is improvement of the diverticulitis of the cecum and ascending colon (black arrow) and only minor signs of liver abscess (arrowhead).


Reference

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