Korean J Nephrol.
1999 Nov;18(6):1013-1016.
A Case of Drug-Induced Chylous Ascites in a Patient Undergoing Continuous
Ambulatory Peritoneal Dialysis
Abstract
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A chylous ascites, especially drug-induced, is very rare complication in CAPD. The diagnostic
criteria for the drug-induced chylous peritoneal dialysate include 1) turbid dialysate
developed within Chrs after the administration of causative drug, 2) no clinical symptoms
being suggestive of peritoneal inflammation, 3) the fluid containing normal leukocyte counts
and being negative for bacterial and fungal culture, and 4) it disappeared spontaneously
after the withdrawal of the assumed causative agent and never recurred thereafter. We report
a case of chylous ascites emerging after use of manidipine, dihydropyridine calcium channel
blocker, in a patient undergoing CAPD. The chylous ascites in that patient was improved after
discontinuation of manidipine.