Korean J Med.  2001 Jun;60(6):593-596.

A case of thrombotic thrombocytopenic purpura in systemic lupus erythematosus

Affiliations
  • 1Department of Internal Medicine, Collage of Medicine, Pusan National University, Pusan, Korea. ksimd@hyowon.pusan.ac.kr

Abstract

Thrombotic thrombocytopenic purpura (TTP) rarely may be seen in association with autoimmune processes such as scleroderma, rheumatoid arthritis, polyarteritis nodosa, Sj gren's syndrome, and systemic lupus erythematosusus (SLE). The diagnosis of TTP as a syndrome distinct from SLE may be challenging, because both processes may present with some or all elements of the classic pentad considered pathognomonic of the former: microangiopathic hemolytic anemia, fever, thrombocytopenia, neurological deficits, and renal abnormalities. We describe a patient with synchronous TTP and SLE, and review the literature.

Keyword

Purpura, thrombotic thrombocytopenic; Lupus erythematosus, systemic

MeSH Terms

Anemia, Hemolytic
Arthritis, Rheumatoid
Diagnosis
Fever
Humans
Lupus Erythematosus, Systemic*
Polyarteritis Nodosa
Purpura, Thrombotic Thrombocytopenic*
Thrombocytopenia
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