Korean J Med.  2009 Jul;77(1):35-51.

New antimicrobials on the horizon

Affiliations
  • 1Division of Infectious Diseases, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.

Abstract

Recently, infections caused by antibiotic-resistant bacteria continue to climb in the community and the hospital around the world. Our current antimicrobial agents are gradually becoming ineffective and a new pipeline of powerful compounds is needed urgently. A number of new antimicrobial compounds are in development, including novel glycopeptides (dalbavancin, telavancin, and oritavancin), daptomycin, tigecycline, ceftobiprole, iclaprim, and doripenem. The article will provide an update on the newly marketed and potentially effective antibacterial agents in the late-stage development pipeline

Keyword

Anti-infective agents; Drug resistance; Investigational new drugs

MeSH Terms

Aminoglycosides
Anti-Bacterial Agents
Anti-Infective Agents
Bacteria
Carbapenems
Cephalosporins
Daptomycin
Drug Resistance
Drugs, Investigational
Glycopeptides
Minocycline
Pyrimidines
Trastuzumab
Aminoglycosides
Anti-Bacterial Agents
Anti-Infective Agents
Carbapenems
Cephalosporins
Daptomycin
Drugs, Investigational
Glycopeptides
Minocycline
Pyrimidines
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