Korean J Leg Med.
2010 Nov;34(2):147-151.
Null and Duplicated Alleles of 17 Y-STR Haplotypes in Koreans and Considerations for Forensic Application
- Affiliations
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- 1Department of Forensic Medicine, Central District Office, National Institute of Scientific Investigation, Daejeon, Korea.
- 2Department of forensic Medicine, Eulji University, Daejeon, Korea. wtlee@eulji.ac.kr
Abstract
- The analysis of Y chromosome polymorphisms has become common place for the identification of male component in forensic cases. In male/female mixtures of many rape cases, Y-STRs are also very useful for the determination of contributors' number. During the analyses of 17 Y-STR haplotypes for forensic applications using the AmpFlSTR(R) Yfiler(TM) system, a number of null and duplicated alleles (40 out of 2144 subjects) were discovered. Interestingly, two haplotypes should focus the attention on forensic interpretation of Y-STR haplotype profiles, because multiple mutational events at various loci can be interpreted as a wrong mixed or allele drop-out profile.
