Korean J Gastrointest Motil.
1999 Nov;5(2):156-161.
Gut Dysmotility in Selective Postganglionic Cholinergic Dysautonomia
- Affiliations
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- 1Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. songcw@kuccnx.korea.ac.kr
- 2Department of Institute of Digestive Disease and Nutrition, Korea University College of Medicine, Seoul, Korea.
Abstract
- Postganglionic cholinergic dysautonomia is a rare disease characterized by impaired secretion of tears and saliva, generalized absence of sweating, lack of cardiac response to carotid massage and atony of the gastrointestinal tract and urinary bladder. Autonomic function tests show the preservation of sympathetic adrenergic functions in contrast to the generalized involvement of postganglionic parasympathetic and sympathetic cholinergic nerves. Recently, we experienced a patient with gut dysmotility in selective postganglionic cholinergic dysautonomia. She is now being treated with bethanechol and milk of magnesia and has experienced minimal symptom improvement.
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