Korean J Gastrointest Endosc.  1999 Jun;19(3):486-490.

A Case of Squamous Cell Carcinoma of the Common Bile Duct

• Kim KS
• Park HB
• Yeo HS
• Kang MW
• Lim YK
• Kang SJ
• Woo YA
• Hong GY
• Ryu SS
• Park JS

Abstract

A 57-year-old female with jaundice and right upper quadrant abdominal pain, was found on exploration to have squamous cell carcinoma of the common bile duct. Squamous cell carcinoma of the common bile duct is a very rare tumor, simulating adenocarcinoma in its clinical presentation and aggressiveness. Although no consistent causative factors for this tumor has been demonstrated, it has been theorized that the normal columnar epithelium of the bile duct under the influence of an inflammatory stimulus, can develop into squamous epithelium with the ongoing process leading to squamous metaplasia, and eventually carcinoma. Cholelithiasis has been implicated as a cause for bile duct cancer, which was manifested in this patient. The prognosis of this carcinoma was grave, despite all forms of surgical and medical management. A case of squamous cell carcinoma of the common bile duct is reported with a review of relevant literature.

Keyword

Squamous cell carcinoma; Common bile duct; Cholelithiasis

MeSH Terms

Abdominal Pain
Adenocarcinoma
Bile Duct Neoplasms
Bile Ducts
Carcinoma, Squamous Cell*
Cholelithiasis
Common Bile Duct*
Epithelium
Female
Humans
Jaundice
Metaplasia
Middle Aged
Prognosis