Korean J Gastrointest Endosc.  2006 Jul;33(1):37-41.

A Case of Photodynamic Therapy as a Curative Treatment of Early Esophageal Cancer

  • 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. choim@catholic.ac.kr


Although the surgical treatment of early esophageal cancer is a well-known curative modality, less invasive endoscopic methods have attracted significant attention recently on account of the fewer postoperative complications, better quality of life and preservation of the integrity of the esophagus. Among the various endoscopic techniques employed, photodynamic therapy (PDT) has been used to allow the selective destruction of malignant tissue through a photochemical effect after the administration of a photosensitizer for curative and palliative treatment purposes. This report describes a case of a 73-year-old man with early esophageal cancer, which had been diagnosed by fluorodeoxyglucose-positron emission tomography (FDG-PET) and endoscopy and a long history of chronic pulmonary diseases such as emphysema and radiation fibrosis. The patient was cured successfully with photodynamic therapy using porfimer sodium as the photosensitizer.


Photodynamic therapy; Early esophageal cancer
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