Korean J Gastrointest Endosc.  2007 Jan;34(1):47-50.

A Case of Giant Brunner's Gland Hamartoma Presenting as Gastrointestinal Hemorrhage

  • 1Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea. king9256@hanmail.net


Brunner's gland hamartoma is also called Brunner's gland adenoma and Brunner's gland hyperplasia of Brunneroma, and it is a rare tumor of the duodenum. This tumor is caused by a benign proliferation of Brunner's glands, and the disease is normally present on the duodenum. These tumors arise mainly in the duodenal bulb and only rarely in the jejunum and proximal ileum. The clinical manifestations are nonspecific gastrointestinal complaints such as bloating or epigastric pain, and the tumor often gives rise to melena or obstruction. We report here on a case of a giant Brunner's gland hamartoma in a 48 year-old woman, and it was treated by endoscopic polypectomy. We also include a review of the related literatures.


Brunner's gland; Hamartoma; Gastrointestinal hemorrhage
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