Korean J Epidemiol.  1997 Dec;19(2):161-179.

Studies on Risk Factors in Cancers of the Breast, Uterine Cervix and Ovary

Affiliations
  • 1Graduate School of Public Health, Chungnam National University, Taejon, Korea.
  • 2Laboratory of Clinical Research, Korea Cancer Center Hospital, Seoul, Korea.

Abstract

This study presents the comparative pattern of risks for cancers of the breast, uterine cervix and ovary in relation to various risk factors based on the data from a case-control study conducted at the Korea Cancer Center Hospital in Seoul between August in 1996 and March in 1997. Included in the analysis were 128 women of breast cancer, 169 women of uterine cevical cancer and 45 of ovarian cancer confirmed by the historical diagnosis. Person interviews were conducted in all cases through standard questionnaire. Data were analyzed using multiple logistic regression, adjusting for potential confounding factors. In cancers of the uterine cervix and ovary, increasing risks were seen in earlier age at first menarch. Statistically significant associations were found with postmenopausal women in cancers of the breast(OR=2.0) and ovary(OR=8.5). The OR increased with late age at postmenopause in postmenopausal women of uterine cervical cancer(OR=7.0). Increasing number of pregnant and livebirths was associated with a higher risk of uterine cervical cancer(OR=2.7, 2.9). The risk of uterine cervical cancer was decreasing with increasing age at first birth(OR=0.2). Among postmenopausal women, the OR increased with BMI in breast cancer. A positive history of breastfeeding was associated with significantly lower risk of breast cancer(OR=0.4). There were no associations with anthropometric measurements(height, weight, BMI), smoking, alcohol intake, menstrual regularity, age at first marriage, number of marriage and induced abortion, and oral contraceptives in cancers of the breast, uterine cervix and ovary. In cancers of the breast and uterine cervix, decreasing risks were seen in intake of fresh fruits, carrot and cabbage.

Keyword

Breast cancer; Uterine cervical cancer; Ovarian cancer; Case-control study; Reproduction; Diet

MeSH Terms

Abortion, Induced
Brassica
Breast Feeding
Breast Neoplasms
Breast*
Case-Control Studies
Cervix Uteri*
Contraceptives, Oral
Daucus carota
Diagnosis
Diet
Female
Fruit
Humans
Korea
Logistic Models
Marriage
Ovarian Neoplasms
Ovary*
Postmenopause
Reproduction
Risk Factors*
Seoul
Smoke
Smoking
Uterine Cervical Neoplasms
Surveys and Questionnaires
Contraceptives, Oral
Smoke
Full Text Links
  • KJE
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr