Korean J Dermatol.  1996 Jun;34(3):476-479.

A Case of Herpes Zoster in a Normal 3 - Month - Old Infant

Affiliations
  • 1Department of Dermatology, Fatima Hospital, Korea.
  • 2Catholic Dermatology Clinic, Taegu, Korea.

Abstract

Herpes zoster in infancy occurs very rarely. And it may be the primary clinical manifestation of reactivation of latent varicella-zoster virus infection acquired transplacentally during intrauterine life. We report a case of herpes zoster in right T2 dermatome in a normal 3-month-old boy, The patient had no history of chickenpox and varicella vaccination. And his mother did not recall herself varicella infection, though she was exposured to chickenpox patient at 7 months of pregnancy. Laboratory findings demonstrated that varicella-zoster Ig-G and Ig-M antibodies were 0.94, 0.12 respectively ( EIA method, negative, <0.8; positive, >1.0) at the second day of vesicular eruption. Fourteen days after vesicular developing, the Ig-G and Ig M titers were rising to 1.92, and 0.47 respectively. His mother's varicella-zoster Ig-G and Ig-M antihodies were 2.64, 0.14 respectively. The baby received acyclovir treatment and the skin lesions healed rapidly without sequela. In this case, although the cause was unclear whether it was a mother-child infection, the patient was suspected subclinical intrauterine varicella-zoster virus infection during pregnancy.

Keyword

Herpes zoster; Infancy

MeSH Terms

Acyclovir
Antibodies
Chickenpox
Herpes Zoster*
Herpesvirus 3, Human
Humans
Infant*
Male
Mothers
Pregnancy
Skin
Vaccination
Acyclovir
Antibodies
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