Korean J Dermatol.  1998 Aug;36(4):742-744.

A Case of Recurrent Urticaria Induced by Tartrazine Present in Antihistamine

• Hur H

Abstract

Antihistamines are commonly used for the treatment of urticaria. Some antihistamines contain dyes and preservatives which have themselves been shown to produce or exacerbate urticaria. Tartrazine is used predominantly as an additive in food and drugs. To stimulate awareness of this problem, the author reports a case of recurrent urticaria induced by tartrazine in an antihistamine in a 25-year-old male patient. His skin lesions recurred after treatment with oral antihistamine containing tartrazine. The provocation tests with 0.1mg of tartrazine and the antihistamine containing tartrazine induced urticaria within two hours. The provocation tests with aspirin and sodium benzoate were negative.

Keyword

Urticaria; Tartazine

MeSH Terms

Adult
Aspirin
Coloring Agents
Histamine Antagonists
Humans
Male
Skin
Sodium Benzoate
Tartrazine*
Urticaria*
Aspirin
Coloring Agents
Histamine Antagonists
Sodium Benzoate
Tartrazine